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On the other hand, the function of xCT is to introduce cysteine for glutathione biosynthesis and antioxidant defense (Wang et al., 2023)

In multiple oxidative stress models of retinal degeneration, elevated GPX4 expression has been shown to protect photoreceptors and RPECs, suggesting that increasing GPX4 expression may represent a potential gene therapy approach for patients with AMD (47, 48)

This directly tackles the root causes of fine lines and wrinkles and sagging

Drawing upon a comprehensive understanding of the aforementioned mechanisms and adopting a translational medicine approach, intervention strategies that target the gut microbiota possess substantial clinical significance